Neurological soft signs in borderline personality disorder and schizophrenia

Patients with BPD have significantly higher NSS levels than HC. NSS in BPD showed significant associations with childhood trauma, supporting a "two-hit" model. Importantly, patients with BPD and SZ may show similar NSS patterns, suggesting that sensorimotor dysfunction is a transdiagnostic phenomenon.

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Publication Details

Journal
Borderline Personality Disorder and Emotion Dysregulation
Published
2025-03-17
DOI
https://doi.org/10.1186/s40479-025-00282-7
Primary Topic
Schizophrenia research and treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Neurological soft signs in borderline personality disorder and schizophrenia

Dušan Hirjak, Stefan Fritze, Fabio Sambataro, Geva A. Brandt et al.
1 links
Borderline Personality Disorder and Emotion Dysregulation
Schizophrenia research and treatment
article

Neurological soft signs in borderline personality disorder and schizophrenia

Dušan Hirjak, Stefan Fritze, Fabio Sambataro, Geva A. Brandt, Katharina M. Kubera, Robert Christian Wolf, Marie‐Luise Otte, Mike M. Schmitgen, Mert İmran Koç, Nadine D. Wolf, Yunus Balcik, Chantal Tech, Yéléna Le Prieult
article en

Abstract

Patients with BPD have significantly higher NSS levels than HC. NSS in BPD showed significant associations with childhood trauma, supporting a "two-hit" model. Importantly, patients with BPD and SZ may show similar NSS patterns, suggesting that sensorimotor dysfunction is a transdiagnostic phenomenon.

Borderline Personality Disorder and Emotion DysregulationVol. 12(1)
University of Padua (IT), Heidelberg University (DE), University Hospital Heidelberg (DE), Central Institute of Mental Health (DE)
Reduced inequalities
Openalex Percentile: Top 94%
Schizophrenia research and treatment
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