Effects of low-dose radiation produced during radiofrequency ablation guided by 3D mapping on mitochondrial apoptosis in diabetic cardiomyocytes
In summary, this study demonstrated that the exposure radiation dose used in radiofrequency ablation guided by 3D mapping was low-dose radiation (LDR), which had no effect on the mitochondrial apoptosis pathway in normal cardiomyocytes and even had a protective effect on cardiomyocytes treated with HG/HL via increased IL-10 levels and the suppression of IL-6, ROS, and mitochondrial damage induced by HG/HL.
Authors
- Binghang Zhang (ORCID: https://orcid.org/0000-0002-9711-9416)
- Jia Gao (ORCID: https://orcid.org/0000-0003-0016-6003)
- Nan Zhang (ORCID: https://orcid.org/0000-0002-3018-5523)
- Meng Sun (ORCID: https://orcid.org/0000-0002-9301-0421)
- Min Guo (ORCID: https://orcid.org/0000-0003-2410-5395)
- Zhijun Meng (ORCID: https://orcid.org/0000-0002-2769-4343)
- Rui Wang (ORCID: https://orcid.org/0000-0002-5843-2178)
Institutions
- Shanxi Medical University (CN)
- First Hospital of Shanxi Medical University (CN)
- Second Hospital of Shanxi Medical University (CN)
Publication Details
- Journal
- BMC Cardiovascular Disorders
- Published
- 2025-03-17
- DOI
- https://doi.org/10.1186/s12872-025-04621-y
- Citations
- 1
- Primary Topic
- Ultrasound and Hyperthermia Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.67