Factors associated with elevated gentamicin trough levels in neonates: a retrospective analysis of dosing and clinical parameters

This study highlights the critical role of dosing frequency, kidney function, and inflammatory status in influencing gentamicin trough levels in neonates. However, all gentamicin trough levels were within the 2 µg/ml threshold.

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Publication Details

Journal
Frontiers in Pediatrics
Published
2025-03-17
DOI
https://doi.org/10.3389/fped.2025.1510838
Primary Topic
Antibiotics Pharmacokinetics and Efficacy
Type
article
Field-Weighted Citation Impact
0.00
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article

Factors associated with elevated gentamicin trough levels in neonates: a retrospective analysis of dosing and clinical parameters

Alexandra Luister, Julian Trah, Chinedu Ulrich Ebenebe, Philipp Deindl et al.
Frontiers in Pediatrics
Antibiotics Pharmacokinetics and Efficacy
article

Factors associated with elevated gentamicin trough levels in neonates: a retrospective analysis of dosing and clinical parameters

Alexandra Luister, Julian Trah, Chinedu Ulrich Ebenebe, Philipp Deindl, Dominique Singer, Claudia Langebrake
article en

Abstract

This study highlights the critical role of dosing frequency, kidney function, and inflammatory status in influencing gentamicin trough levels in neonates. However, all gentamicin trough levels were within the 2 µg/ml threshold.

Frontiers in PediatricsVol. 13
Universität Hamburg (DE), University Medical Center Hamburg-Eppendorf (DE)
Openalex Percentile: Top 94%
Antibiotics Pharmacokinetics and Efficacy
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Factors associated with elevated gentamicin trough levels in neonates: a retrospective analysis of dosing and clinical parameters — Alexandra Luister, Julian Trah, et al. · Frontiers in Pediatrics (2025) | TGRS Research Map | TGRS