T-cell activation and senescence in asymptomatic HIV/Leishmania infantum co-infection
Although asymptomatic HIV/Leish subjects had CD4+ and CD8+ T cells similar to HIV alone, their CD8+T cells had increased activation and senescence which could contribute to risk of developing VL.
Authors
- Richard D. Pearson (ORCID: https://orcid.org/0000-0002-7386-3566)
- Amanda de Albuquerque Lopes Machado
- Mary E. Wilson (ORCID: https://orcid.org/0000-0001-8680-7275)
- Eliana L. Nascimento
- Manoella do Monte Alves (ORCID: https://orcid.org/0000-0003-2485-3502)
- Iraci Duarte de Lima
- Marshall J. Glesby (ORCID: https://orcid.org/0000-0002-2145-148X)
- Eliardo G. Costa (ORCID: https://orcid.org/0000-0003-4528-0379)
- Selma M. B. Jerônimo (ORCID: https://orcid.org/0000-0002-4784-9904)
- Carolina de Oliveira Mendes-Aguiar (ORCID: https://orcid.org/0000-0001-9601-8376)
- Iara Marques de Medeiros
- José Wilton Queiroz
- Gloria Regina de Góis Monteiro
Institutions
- University of Iowa (US)
- Cornell University (US)
- Universidade Federal do Rio Grande do Norte (BR)
- University of Virginia (US)
Publication Details
- Journal
- PLoS neglected tropical diseases
- Published
- 2025-03-17
- DOI
- https://doi.org/10.1371/journal.pntd.0012848
- Citations
- 3
- Primary Topic
- Research on Leishmaniasis Studies
- Type
- article
- Field-Weighted Citation Impact
- 5.64
Funders
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Instituto Nacional de Ciência e Tecnologia de Doenças Tropicais