Digging into the Cause of Drug-Induced Thrombocytopenia: A Case Report

Thrombocytopenia can be caused by various etiologies, one of which is immune-mediated destruction. Within the realm of immune thrombocytopenia, there can be multiple pathways and mechanisms that lead to platelet destruction. Finding the exact mechanism can be a crucial diagnostic step in deciding the most appropriate treatment of the platelet loss and in the therapeutic planning of a patient's comorbidities, especially in patients with malignancies. In this case report, we describe a patient with metastatic clear cell renal cell carcinoma who developed acute thrombocytopenia while preparing to initiate therapy for his malignancy.

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Publication Details

Journal
Journal of the Advanced Practitioner in Oncology
Published
2025-03-17
DOI
https://doi.org/10.6004/jadpro.2025.16.2.3
Primary Topic
Platelet Disorders and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Digging into the Cause of Drug-Induced Thrombocytopenia: A Case Report

Christopher Selby, Vivian Pham
Journal of the Advanced Practitioner in Oncology
Platelet Disorders and Treatments
article

Digging into the Cause of Drug-Induced Thrombocytopenia: A Case Report

Christopher Selby, Vivian Pham
article en

Abstract

Thrombocytopenia can be caused by various etiologies, one of which is immune-mediated destruction. Within the realm of immune thrombocytopenia, there can be multiple pathways and mechanisms that lead to platelet destruction. Finding the exact mechanism can be a crucial diagnostic step in deciding the most appropriate treatment of the platelet loss and in the therapeutic planning of a patient's comorbidities, especially in patients with malignancies. In this case report, we describe a patient with metastatic clear cell renal cell carcinoma who developed acute thrombocytopenia while preparing to initiate therapy for his malignancy.

Journal of the Advanced Practitioner in OncologyVol. 16(2)
Southwestern Medical Center (US), Southwestern Medical Center (US), The University of Texas Southwestern Medical Center (US)
Openalex Percentile: Top 93%
Platelet Disorders and Treatments
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