TLR2 activates AP‐1 to facilitate CTGF transcription and stimulate doxorubicin‐induced myocardial injury
TLR2 activates AP-1 which cooperates with SOX10 to promote CTGF transcription and subsequently activate the MAPK pathway, thereby stimulating Dox-induced myocardial injury.
Authors
- Xinyong Cai (ORCID: https://orcid.org/0000-0002-5243-5773)
- Pengtao Zou
- Lang Hong
- Yuliang Zhan (ORCID: https://orcid.org/0000-0003-0506-3716)
- Songtao Liu (ORCID: https://orcid.org/0000-0003-3114-7163)
- Yanmei Chen
- Liang Shao (ORCID: https://orcid.org/0000-0003-3092-6229)
Institutions
- First Affiliated Hospital of Jiangxi Medical College (CN)
- Jiangxi Provincial People's Hospital (CN)
Publication Details
- Journal
- British Journal of Pharmacology
- Published
- 2025-03-17
- DOI
- https://doi.org/10.1111/bph.17423
- Citations
- 4
- Primary Topic
- Connective Tissue Growth Factor Research
- Type
- article
- Field-Weighted Citation Impact
- 3.22
Funders
- National Natural Science Foundation of China