Excipient Lung Disease and Fatal Outcome Among Young Adults: A Case Series on the Hidden Dangers of Intravenous Drug Abuse in India

When injected, excipients such as talc and microcrystalline cellulose lead to granulomatous reactions and pulmonary complications. The study highlights the prevalence of ELD among young adults in India and the challenges in diagnosing this condition due to its nonspecific presentation and lack of disclosure of drug abuse history. Effective public health measures and stricter regulation of prescription drugs are crucial in preventing ELD-related deaths. This study underscores the severe health risks associated with IV drug abuse of oral tablets, leading to ELD. The findings emphasize the need for enhanced awareness, accurate documentation, and preventive strategies to address the rising substance abuse among youth in India.

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Publication Details

Journal
Annals of African Medicine
Published
2025-03-17
DOI
https://doi.org/10.4103/aam.aam_210_24
Primary Topic
Forensic Toxicology and Drug Analysis
Type
article
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article

Excipient Lung Disease and Fatal Outcome Among Young Adults: A Case Series on the Hidden Dangers of Intravenous Drug Abuse in India

Venkatesh Janarthanan, Sankaran Narayanan, S Senthil Kumaran, Rahul Raguram et al.
Annals of African Medicine
Forensic Toxicology and Drug Analysis
article

Excipient Lung Disease and Fatal Outcome Among Young Adults: A Case Series on the Hidden Dangers of Intravenous Drug Abuse in India

Venkatesh Janarthanan, Sankaran Narayanan, S Senthil Kumaran, Rahul Raguram, Dibya Prakash, R Balaji
article en

Abstract

When injected, excipients such as talc and microcrystalline cellulose lead to granulomatous reactions and pulmonary complications. The study highlights the prevalence of ELD among young adults in India and the challenges in diagnosing this condition due to its nonspecific presentation and lack of disclosure of drug abuse history. Effective public health measures and stricter regulation of prescription drugs are crucial in preventing ELD-related deaths. This study underscores the severe health risks associated with IV drug abuse of oral tablets, leading to ELD. The findings emphasize the need for enhanced awareness, accurate documentation, and preventive strategies to address the rising substance abuse among youth in India.

Annals of African MedicineVol. 24(4)
Stanley Medical College (IN), All India Institute of Medical Sciences (IN)
Good health and well-being
Openalex Percentile: Top 95%
Forensic Toxicology and Drug Analysis
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