Anti-breast cancer potential of thieno-pyrimidine derivatives as VEGFR-2 inhibitors
Compound <b>6b</b> exhibits strong VEGFR-2 inhibition, potent anti-cancer effects, and a favorable toxicity profile, highlighting its potential for further therapeutic development.
Authors
- Ibrahim H. Eissa (ORCID: https://orcid.org/0000-0002-6955-2263)
- Aisha A. Alsfouk (ORCID: https://orcid.org/0000-0003-4497-5013)
- Maged Mohammed Saleh Al Ward (ORCID: https://orcid.org/0000-0003-1865-8110)
- Reda G. Yousef (ORCID: https://orcid.org/0000-0003-3709-1930)
- Hazem Elkady (ORCID: https://orcid.org/0000-0003-0893-6703)
- Souad A. El‐Metwally (ORCID: https://orcid.org/0000-0002-3040-9283)
- Eslam B. Elkaeed (ORCID: https://orcid.org/0000-0002-2546-8035)
- Dalal Z. Husein (ORCID: https://orcid.org/0000-0001-7552-0914)
- Ahmed M. Metwaly (ORCID: https://orcid.org/0000-0001-8566-1980)
- Fatma G. Amin (ORCID: https://orcid.org/0000-0003-2615-7375)
- Mustafa A. Al-Qadhi
Institutions
- Princess Nourah bint Abdulrahman University (SA)
- Alfaisal University (SA)
- Nile Valley University (SD)
- Higher Technological Institute (EG)
- Sana'a University (YE)
- Al-Azhar University (EG)
- South Valley University (EG)
- Merit Network (US)
- Al-Azhar University (ID)
- Al-Razi University (YE)
- New Valley University
- Almaarefa University
- Alexandria University (EG)
- Sohag University (EG)
Publication Details
- Journal
- Future Medicinal Chemistry
- Published
- 2025-03-17
- DOI
- https://doi.org/10.1080/17568919.2025.2479422
- Citations
- 3
- Primary Topic
- Synthesis and biological activity
- Type
- article
- Field-Weighted Citation Impact
- 2.81
Funders
- Princess Nourah Bint Abdulrahman University