Unusual Sole Extramedullary Diffuse Kidney Involvement in Multiple Myeloma Initial Workup Using 2-[18F]FDG-PET/CT Imaging
2-[ 18 F]fluorodeoxyglucose-positron emission tomography with computed tomography (2-[ 18 F]FDG-PET/CT) in multiple myeloma (MM) allows the detection of extramedullary disease (EMD), which is scarce at initial workup. We report here for the first time uncommon 2-[ 18 F]FDG-PET/CT imaging results of a 63-year-old woman with newly diagnosed MM and sole diffuse kidney EMD revealed by a significantly increased renal volume and intense/diffuse bilateral renal cortical uptake without visualization of the urinary excretory cavities then confirmed by kidney biopsy. This case highlights the possibility of a diffuse organ involvement different from the typical imaging pattern of nodular plasmacytoma lesions in soft tissues.
Authors
- Françoise Kraeber‐Bodéré (ORCID: https://orcid.org/0000-0002-3417-0759)
- Chloé Antier (ORCID: https://orcid.org/0000-0001-6227-8540)
- Bastien Jamet (ORCID: https://orcid.org/0000-0002-2145-9182)
- Cyrille Touzeau (ORCID: https://orcid.org/0000-0003-0275-2575)
- Philippe Moreau (ORCID: https://orcid.org/0000-0003-1780-8746)
Institutions
- Centre National de la Recherche Scientifique (FR)
- Inserm (FR)
- Centre de Recherche en Cancérologie et Immunologie Intégrée Nantes Angers (FR)
- Nantes Université (FR)
Publication Details
- Journal
- Clinical Nuclear Medicine
- Published
- 2025-03-17
- DOI
- https://doi.org/10.1097/rlu.0000000000005847
- Primary Topic
- Multiple Myeloma Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00