Cognitive outcomes and performance of patients diagnosed and treated for N-Methyl-D-Aspartate receptor antibody-mediated (NMDAR) encephalitis compared with patients with schizophrenia and healthy controls
Study findings suggest cognitive performance in patients treated for NMDAR encephalitis approaches normal over time. Prompt treatment with immunotherapy is associated with improved cognitive outcomes. Psychiatric services should be aware of the clinical features of autoimmune encephalitis.
Authors
- Aiden Corvin (ORCID: https://orcid.org/0000-0001-6717-4089)
- David Cotter (ORCID: https://orcid.org/0000-0003-4308-0648)
- Colin P. Doherty (ORCID: https://orcid.org/0000-0002-8869-8567)
- Kieran C. Murphy (ORCID: https://orcid.org/0000-0003-2930-4465)
- Gary J Donohoe (ORCID: https://orcid.org/0000-0003-3037-7426)
- Elijah Chaila
- April Hargreaves
- Shane Smyth
- David Mothersill (ORCID: https://orcid.org/0000-0003-3013-4088)
- Dominick Jh McCabe
- Peter Boers
- Daniel J. Costello (ORCID: https://orcid.org/0000-0001-6023-8246)
- Brian Sweeney
- Eric Kelleher (ORCID: https://orcid.org/0000-0002-1860-9493)
- Helen Barry
Institutions
- National College of Ireland (IE)
- Royal College of Surgeons in Ireland (IE)
- Ollscoil na Gaillimhe – University of Galway (IE)
- Trinity College Dublin (IE)
- University College Cork (IE)
- Beaumont Hospital (IE)
- Cork University Hospital (IE)
- University Hospital Limerick (IE)
- Tallaght University Hospital (IE)
- Mater Misericordiae University Hospital (IE)
Publication Details
- Journal
- Psychiatry Research Neuroimaging
- Published
- 2025-03-17
- DOI
- https://doi.org/10.1016/j.pscychresns.2025.111983
- Citations
- 2
- Primary Topic
- Autoimmune Neurological Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.78
Funders
- Irish Institute of Clinical Neuroscience