INFLUENCE OF DRUG DELIVERY SYSTEMS ON THE SAFETY AND EFFECTIVENESS PROFILE OF RIBAVIRIN
Ribavirin is an antiviral drug with a wide spectrum of pharmacological activity. The development of drug delivery systems that increase the safety and effectiveness of ribavirin has been the subject of scientific research for decades. The aim of this article is to examine the published information on this topic, evaluate it according to several criteria, and outline the primary perspectives on this subject within the fields of pharmacy and pharmacology. The results of the evaluation indicate that, despite the extensive and ongoing discourse surrounding the potential modifications to ribavirin within the international scientific community, the majority of publications adopt an illustrative approach. Many relevant and promising applied studies require further development, comprehensive biopharmaceutical indicator testing, rigorous clinical efficacy assessment, and a thorough evaluation of patient compliance.
Authors
- Е. О. Бахрушина (ORCID: https://orcid.org/0000-0001-8695-0346)
- О. И. Степанова (ORCID: https://orcid.org/0000-0002-9885-3727)
- Iosif B. Mikhel (ORCID: https://orcid.org/0000-0002-2866-0049)
- Е. А. Smolyarchuk (ORCID: https://orcid.org/0000-0002-2615-7167)
- I. I. Krasnyuk
- S. A. TITOVA
Institutions
- Sechenov University (RU)
Publication Details
- Journal
- International Journal of Applied Pharmaceutics
- Published
- 2025-03-07
- DOI
- https://doi.org/10.22159/ijap.2025v17i2.52864
- Primary Topic
- Hepatitis C virus research
- Type
- article
- Field-Weighted Citation Impact
- 0.00