Clinical and laboratory markers defining MIS-C and hyperinflammation in COVID-19: a cross-sectional study in a tertiary hospital
This is an original study comparing clinical and laboratory findings between MIS-C and hyperinflammation due to COVID. Altered mental status is more frequently associated with MIS-C while respiratory symptoms are associated with hyperinflammation. In addition, regarding laboratory tests, there is hypoalbuminemia, increase in serum troponin, BNP, and D-dimers specially in the MIS-C group and hyperferritinemia in the hyperinflammation group. Further studies are needed to assess the cutoff point of biological markers such as BNP, troponin, and d-dimers for diagnosis and/or prognosis in the pediatric population with MIS-C.
Authors
- Paulo Roberto Antonacci Carvalho (ORCID: https://orcid.org/0000-0002-4197-3541)
- Sandra Helena Machado (ORCID: https://orcid.org/0000-0001-6142-2934)
- Ana Paula Radünz Vieira (ORCID: https://orcid.org/0000-0002-4009-4019)
- Taís Sica da Rocha (ORCID: https://orcid.org/0000-0002-6042-8370)
Institutions
- Universidade Federal do Rio Grande do Sul (BR)
- Hospital de Clínicas de Porto Alegre (BR)
Publication Details
- Journal
- Advances in Rheumatology
- Published
- 2025-03-17
- DOI
- https://doi.org/10.1186/s42358-025-00447-6
- Citations
- 2
- Primary Topic
- Kawasaki Disease and Coronary Complications
- Type
- article
- Field-Weighted Citation Impact
- 4.01