Green and Efficient Synthesis of Novel Pyrazole based Hydrazineyl-Thiazole Derivatives

A green and efficient protocol for the synthesis of novel pyrazole based hydrazineyl-thiazole derivatives via a two-step procedure is reported. The reaction has been catalyzed by p-TSA using ethanol as green solvent. The present protocol offers several advantages such as broad substrate scope, operational simplicity, high yields and use of environmentally benign solvent.

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Publication Details

Journal
International Journal of Scientific Research in Science and Technology
Published
2025-03-15
DOI
https://doi.org/10.32628/ijsrst25122220
Primary Topic
Synthesis and biological activity
Type
article
Field-Weighted Citation Impact
0.00
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article

Green and Efficient Synthesis of Novel Pyrazole based Hydrazineyl-Thiazole Derivatives

Wilson B. Chandane, Dipak P. Hiwarale, Shivanand G. Sonkamble, Dattatraya Raut
International Journal of Scientific Research in Science and Technology
Synthesis and biological activity
article

Green and Efficient Synthesis of Novel Pyrazole based Hydrazineyl-Thiazole Derivatives

Wilson B. Chandane, Dipak P. Hiwarale, Shivanand G. Sonkamble, Dattatraya Raut
article en

Abstract

A green and efficient protocol for the synthesis of novel pyrazole based hydrazineyl-thiazole derivatives via a two-step procedure is reported. The reaction has been catalyzed by p-TSA using ethanol as green solvent. The present protocol offers several advantages such as broad substrate scope, operational simplicity, high yields and use of environmentally benign solvent.

International Journal of Scientific Research in Science and TechnologyVol. 12(2)
Shivaji University (IN), Bhagat Phool Singh Mahila Vishwavidyalaya (IN), Sanskriti Samvardhan Mandal (IN)
Openalex Percentile: Top 96%
Synthesis and biological activity
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