Photoinduced Diazo Carbene-Promoted C(sp<sup>3</sup>)–H Oxidative Cross-Coupling Reaction for α-Triazolation of Isochromans
A photocatalytic diazo triplet carbene-promoted C(sp<sup>3</sup>)-H oxidative coupling of isochromans and triazoles was developed in up to 83% yield at room temperature in air. The radical-like triplet carbenes were used as efficient HAT acceptors, and the possible synergistic HAT enabled the unprecedented process with a high regioselectivity.
Authors
- Shunying Liu (ORCID: https://orcid.org/0000-0002-3894-757X)
- Xiao Tang (ORCID: https://orcid.org/0000-0001-9545-247X)
- Xiang Wu (ORCID: https://orcid.org/0000-0001-5428-9063)
- Jinhua Liu (ORCID: https://orcid.org/0000-0002-4031-3031)
Institutions
- East China Normal University (CN)
Publication Details
- Journal
- The Journal of Organic Chemistry
- Published
- 2025-03-17
- DOI
- https://doi.org/10.1021/acs.joc.4c02722
- Citations
- 3
- Primary Topic
- Catalytic C–H Functionalization Methods
- Type
- article
- Field-Weighted Citation Impact
- 2.81
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Chongqing