Interferon Regulatory Factor 3 Exacerbates the Severity of COVID-19 in Mice
These data indicated that IRF3 played a detrimental role in murine COVID-19 associated with changes in IFN-β and inflammatory cytokines.
Authors
- Nawar Hakim
- Dinesh G. Goswami (ORCID: https://orcid.org/0000-0003-3077-1642)
- Pedro M. Palermo (ORCID: https://orcid.org/0000-0002-7471-0801)
- Luiz F. Garcia
- Douglas M. Watts (ORCID: https://orcid.org/0000-0003-0225-4357)
- Alok Dwivedi (ORCID: https://orcid.org/0000-0003-4574-1761)
- Wendy E. Walker (ORCID: https://orcid.org/0000-0001-7634-9629)
Institutions
- Mercer University (US)
Publication Details
- Journal
- Critical Care Explorations
- Published
- 2025-03-01
- DOI
- https://doi.org/10.1097/cce.0000000000001225
- Primary Topic
- SARS-CoV-2 and COVID-19 Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00