The <i>optrA</i>, <i>cfr</i>(D) and <i>vanA</i> genes are co-located on linear plasmids in linezolid- and vancomycin-resistant enterococcal clinical isolates in Italy
To the best of our knowledge this is the first report on the occurrence of a linear plasmid in E. faecalis. Linear plasmids can play a key role in the spread of oxazolidinone and glycopeptide resistance with serious consequences for public health.
Authors
- Silvia Di Lodovico (ORCID: https://orcid.org/0000-0001-9281-5028)
- Xiang‐Dang Du (ORCID: https://orcid.org/0000-0001-7431-7607)
- Andrea Brenciani (ORCID: https://orcid.org/0000-0001-5191-3908)
- Giovanni Gherardi (ORCID: https://orcid.org/0000-0001-6010-3157)
- Carla Vignaroli (ORCID: https://orcid.org/0000-0002-0993-5967)
- Mara Di Giulio (ORCID: https://orcid.org/0000-0002-8375-9404)
- Sonia Nina Coccitto (ORCID: https://orcid.org/0000-0001-7123-3408)
- Marzia Cinthi
- Anna Teresa Palamara (ORCID: https://orcid.org/0000-0001-8330-4381)
- Eleonora Giovanetti (ORCID: https://orcid.org/0000-0002-9427-8091)
- Serena Simoni
Institutions
- Marche Polytechnic University (IT)
- Università Campus Bio-Medico (IT)
- Istituto Superiore di Sanità (IT)
- University of Chieti-Pescara (IT)
- Henan Agricultural University (CN)
Publication Details
- Journal
- Journal of Antimicrobial Chemotherapy
- Published
- 2025-03-17
- DOI
- https://doi.org/10.1093/jac/dkaf082
- Citations
- 11
- Primary Topic
- Antimicrobial Resistance in Staphylococcus
- Type
- article
- Field-Weighted Citation Impact
- 15.36