Maternal plasma cell-free DNA nucleosome footprints can reveal changes in gene expression profiles during pregnancy and pre-eclampsia
The depth of the cfDNA nucleosome footprint in maternal plasma can be used to reflect changes in the gene expression profile during pregnancy and pre-eclampsia. The plasma cfDNA nucleosome footprint is a potential non-invasive biomarker for pregnancy and placental-origin pregnancy complications.
Authors
- Zhiwei Guo (ORCID: https://orcid.org/0000-0001-8868-6913)
- Xingyu Wei (ORCID: https://orcid.org/0000-0001-6603-2636)
- Xuexi Yang (ORCID: https://orcid.org/0000-0002-3513-6501)
- Fenxia Li (ORCID: https://orcid.org/0000-0003-1814-1357)
- Kun Li (ORCID: https://orcid.org/0000-0002-2026-9969)
- Shijing Lu
- Min Zhang (ORCID: https://orcid.org/0000-0003-1027-7196)
- Chao Sheng (ORCID: https://orcid.org/0000-0001-6917-7865)
- Wenbo Hao (ORCID: https://orcid.org/0000-0003-3850-6501)
Institutions
- Nanfang Hospital (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- BMC Pregnancy and Childbirth
- Published
- 2025-03-17
- DOI
- https://doi.org/10.1186/s12884-025-07453-y
- Citations
- 2
- Primary Topic
- Pregnancy and preeclampsia studies
- Type
- article
- Field-Weighted Citation Impact
- 4.11