Gastroepiploic Vascularized Lymph Node Transfer for Extremity Lymphedema: Tips and Insights from Extensive Clinical Experience

<i>Background and Objectives</i>: Lymphedema is a chronic and progressive condition that leads to significant morbidity, including recurrent infections, fibrosis, and functional limitations. Conservative treatments often offer limited relief, particularly in severe cases. Vascularized lymph node transfer (VLNT), especially using the gastroepiploic lymph node flap, has emerged as a promising intervention. This study evaluates the long-term outcomes of gastroepiploic VLNT combined with suction-assisted lipectomy (SAL) for extremity lymphedema. <i>Materials and Methods</i>: A retrospective review was conducted on 53 patients treated for lymphedema at our clinic in Taiwan from January 2016 to August 2023. The inclusion criteria required patients to have persistent lymphedema for at least six months despite conservative treatment. VLNT was performed using a laparoscopic approach, and postoperative assessments included limb circumference measurements, lymphoscintigraphy, and tonicity evaluations. <i>Results</i>: Follow-up data were collected for a minimum of 12 months. At a mean follow-up of 14.2 months, significant reductions in limb circumference were observed-35.5% ± 24.9% for upper limbs and 32.2% ± 4.5% for lower limbs. Tonicity improved by 6.2%, and no cellulitis episodes were reported post-surgery. Minor complications included hematoma and sensory changes, with no major donor-site morbidity. Lymphoscintigraphy confirmed improved lymphatic drainage. <i>Conclusions</i>: Gastroepiploic VLNT combined with SAL is an effective and safe treatment for severe extremity lymphedema, providing significant improvements in limb size and tissue tonicity. This technique offers a promising solution for refractory cases.