The impact of different cervical planning target volume designs on efficacy and toxicity in nasopharyngeal carcinoma: a single-center retrospective study
The 2-PTV regimen achieved equivalent survival outcomes while significantly reducing treatment-related toxicities compared to the 3-PTV approach. These results suggest that the 2-PTV strategy may offer a more favorable therapeutic profile for NPC patients, particularly in minimizing severe dermatitis and xerostomia.
Authors
- Rong Shi (ORCID: https://orcid.org/0000-0002-5152-3026)
- Baofeng Li (ORCID: https://orcid.org/0000-0002-7170-5804)
- Li Gao (ORCID: https://orcid.org/0000-0002-5816-5970)
- Sichao Liang (ORCID: https://orcid.org/0000-0001-6743-6130)
- Fan Tang (ORCID: https://orcid.org/0000-0003-3074-2198)
- Sheng-Hui Wang (ORCID: https://orcid.org/0000-0003-2929-9774)
- Huimin Wang (ORCID: https://orcid.org/0000-0002-3955-3687)
- Yanting Zhang
- Bei Chen (ORCID: https://orcid.org/0000-0001-9087-012X)
- Lin Wang (ORCID: https://orcid.org/0009-0001-0933-0220)
- Zhiting Chen (ORCID: https://orcid.org/0000-0003-1495-4772)
Institutions
- Nanfang Hospital (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-03-17
- DOI
- https://doi.org/10.1186/s12885-025-13865-y
- Citations
- 1
- Primary Topic
- Head and Neck Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.85
Funders
- National Natural Science Foundation of China
- National Natural Science Foundation of China-Guangdong Joint Fund