Visualization of P2X7 Receptors in Living Human Gliomas: An 18F-GSK1482160 PET Imaging and Neuropathology Study
The first-in-man study of P2X7R PET demonstrated that PET with 18F-GSK1482160 and 11C-MET provides complementary information, characterizing tumor heterogeneity and the cellular composition of the microenvironment in untreated gliomas.
Authors
- Wendi Zhou (ORCID: https://orcid.org/0000-0002-2644-0675)
- Fang Xie (ORCID: https://orcid.org/0000-0003-2667-281X)
- Yihui Guan (ORCID: https://orcid.org/0000-0003-3001-7965)
- Junbin Han (ORCID: https://orcid.org/0000-0002-2781-7710)
- Yifan Yuan (ORCID: https://orcid.org/0000-0003-1072-5825)
- Tao Hua (ORCID: https://orcid.org/0000-0002-8555-5421)
- Qi Huang (ORCID: https://orcid.org/0000-0002-9425-6618)
- Liang Chen (ORCID: https://orcid.org/0000-0002-2373-5363)
- Kun He (ORCID: https://orcid.org/0000-0002-6969-3488)
- Qi Yue (ORCID: https://orcid.org/0000-0003-1841-0449)
- Yingfang He (ORCID: https://orcid.org/0000-0002-2813-425X)
- Ying Mao (ORCID: https://orcid.org/0000-0001-8055-115X)
Institutions
- Fudan University (CN)
- Center for Excellence in Brain Science and Intelligence Technology (CN)
- National Center for Spinal Disorders (HU)
- Regenerative Medicine Institute (MX)
- Obstetrics and Gynecology Hospital of Fudan University (CN)
- Huashan Hospital (CN)
Publication Details
- Journal
- Clinical Cancer Research
- Published
- 2025-03-17
- DOI
- https://doi.org/10.1158/1078-0432.ccr-24-2830
- Citations
- 9
- Primary Topic
- Adenosine and Purinergic Signaling
- Type
- article
- Field-Weighted Citation Impact
- 10.06