The Prognostic, Predictive and Clinicopathological Implications of KRT81/HNF1A- and GATA6-Based Transcriptional Subtyping in Pancreatic Cancer
Transcriptional subtypes have differential responses to palliative and adjuvant gemcitabine-based chemotherapy and may change during disease progression. Both employed subtyping marker panels are equivalent and may be used to inform clinical therapy decisions.
Authors
- Melanie Alexandra Palm
- Steffen Ormanns (ORCID: https://orcid.org/0000-0002-0754-9034)
- Sai Agash Surendran
- Volker Heinemann (ORCID: https://orcid.org/0000-0002-1349-3321)
- Michael Haas (ORCID: https://orcid.org/0000-0001-6745-7177)
- Stefan Boeck (ORCID: https://orcid.org/0000-0002-1922-2127)
- Michael Guenther (ORCID: https://orcid.org/0009-0001-5091-5060)
- Leah Steinke
- I. Liou
Institutions
- Innsbruck Medical University (AT)
- Tirol Kliniken (AT)
- München Klinik Neuperlach (DE)
- Ludwig-Maximilians-Universität München (DE)
Publication Details
- Journal
- Biomolecules
- Published
- 2025-03-17
- DOI
- https://doi.org/10.3390/biom15030426
- Citations
- 3
- Primary Topic
- Pancreatic and Hepatic Oncology Research
- Type
- article
- Field-Weighted Citation Impact
- 3.14