The Sm14+GLA-SE Recombinant Vaccine Against Schistosoma mansoni and S. haematobium in Adults and School Children: Phase II Clinical Trials in West Africa

Overall, the Sm14+GLA-SE vaccine is safe and highly immunogenic, with a clearly protective potential against schistosomiasis, supporting progression to the next Phase III clinical trials.

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Institutions

Publication Details

Journal
Vaccines
Published
2025-03-16
DOI
https://doi.org/10.3390/vaccines13030316
Citations
6
Primary Topic
Parasites and Host Interactions
Type
article
Field-Weighted Citation Impact
12.29

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article

The Sm14+GLA-SE Recombinant Vaccine Against Schistosoma mansoni and S. haematobium in Adults and School Children: Phase II Clinical Trials in West Africa

Marília Sirianni dos Santos Almeida, Daniella Arêas Mendes‐da‐Cruz, Amadou T. Ly, Rokhaya Diagne et al.
6 citations
Vaccines
Parasites and Host Interactions
12.29
article

The Sm14+GLA-SE Recombinant Vaccine Against Schistosoma mansoni and S. haematobium in Adults and School Children: Phase II Clinical Trials in West Africa

Marília Sirianni dos Santos Almeida, Daniella Arêas Mendes‐da‐Cruz, Amadou T. Ly, Rokhaya Diagne, Mı́riam Tendler, Seynabou Ndiaye, Miryam Marroquin-Quelopana, Jacques Noël Tendeng, Wilson Savino, Rhea N. Coler, Steven G. Reed, Anne‐Marie Schacht, Carolina V. Messias, Tatiane dos Santos, Doudou Diop, Modou Diop, Gilles Riveau, Celso R. Ramos, Jean‐Pierre Dompnier, Juçara de Carvalho Parra, Abdoulaye Mbengue, Marieme Guisse
article en
6 citations

Abstract

Overall, the Sm14+GLA-SE vaccine is safe and highly immunogenic, with a clearly protective potential against schistosomiasis, supporting progression to the next Phase III clinical trials.

VaccinesVol. 13(3)
Université Gaston Berger (SN), Centre National de la Recherche Scientifique (FR), Center for Infectious Disease Research (US), Infectious Disease Research Institute (US), Inserm (FR), University of Washington (US), Université de Lille (FR), Institut Pasteur de Lille (FR), Ministère de la Santé Publique et Action Sociale (SN), Center for Infection and Immunity of Lille (FR), Espoir pour la Sante (SN), Biotech (Brazil) (BR), Fundação Oswaldo Cruz (BR)
Fundação Oswaldo Cruz
Good health and well-being
Openalex Percentile: Top 1%
Parasites and Host Interactions
12.29
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