Exploring Mechanisms and Biomarkers of Breast Cancer Invasion and Migration: An Explainable Gene–Pathway–Compounds Neural Network
GPC-Net is among the pioneering deep neural networks that incorporate pathways and compounds, aiming to balance interpretability and performance. It is expected to offer a more convenient approach for future biomedical research.
Authors
- Ling Qiu (ORCID: https://orcid.org/0000-0002-0734-8144)
- Jie Wu (ORCID: https://orcid.org/0009-0001-1489-1604)
- Dandan Sun
- Yichen Ma (ORCID: https://orcid.org/0009-0003-4226-4880)
- Xia Qian (ORCID: https://orcid.org/0009-0000-6073-0679)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
Publication Details
- Journal
- Cancer Medicine
- Published
- 2025-03-01
- DOI
- https://doi.org/10.1002/cam4.70769
- Citations
- 1
- Primary Topic
- Bioinformatics and Genomic Networks
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- National Natural Science Foundation of China