The IL-6/STAT3 Signaling Pathway Is Involved in Radiotherapy-Mediated Upregulation of PD-L1 in Esophageal Cancer.

Radiotherapy significantly upregulates PD-L1 through the IL-6/STAT3 signaling pathway, suggesting that anti-PD-1/PD-L1 immunotherapy combined with radiotherapy may improve the treatment for ESCC.

Authors

Xuezhou Pang
Yang Shen (ORCID: https://orcid.org/0000-0001-6607-7818)
Yu He (ORCID: https://orcid.org/0000-0003-4898-5518)
Daiyuan Ma (ORCID: https://orcid.org/0000-0002-0757-9487)
Yichen Zhou (ORCID: https://orcid.org/0000-0002-0596-2087)
Honglei Zhu

Institutions

Affiliated Hospital of North Sichuan Medical College (CN)

Publication Details

Journal: PubMed
Published: 2025-01-01
Citations: 1
Primary Topic: Esophageal Cancer Research and Treatment
Type: article
Field-Weighted Citation Impact: 2.01

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article

The IL-6/STAT3 Signaling Pathway Is Involved in Radiotherapy-Mediated Upregulation of PD-L1 in Esophageal Cancer.

Xuezhou Pang, Yang Shen, Yu He, Daiyuan Ma et al.

Jan 1, 2025

1 citations

PubMed

Esophageal Cancer Research and Treatment

2.01

article

The IL-6/STAT3 Signaling Pathway Is Involved in Radiotherapy-Mediated Upregulation of PD-L1 in Esophageal Cancer.

Xuezhou Pang, Yang Shen, Yu He, Daiyuan Ma, Yichen Zhou, Honglei Zhu

January 1, 2025article en

1 citations

Abstract

Radiotherapy significantly upregulates PD-L1 through the IL-6/STAT3 signaling pathway, suggesting that anti-PD-1/PD-L1 immunotherapy combined with radiotherapy may improve the treatment for ESCC.

PubMedVol. 55(1)

Affiliated Hospital of North Sichuan Medical College (CN)

Openalex Percentile: Top 18%

Esophageal Cancer Research and Treatment

2.01

OpenAlex

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The IL-6/STAT3 Signaling Pathway Is Involved in Radiotherapy-Mediated Upregulation of PD-L1 in Esophageal Cancer. — Xuezhou Pang, Yang Shen, et al. · PubMed (2025) | TGRS Research Map | TGRS