Adipose Mesenchymal Stem Cell Exosomes Regulate Ferroptosis via ATF3 to Attenuate Acute Myocardial Infarction.
Exo derived from AD-MSCs can inhibit the expression of ATF3, promote the transport of Fe<sup>2+</sup> by SLC7A11/Xct system, thus inhibiting the ferroptosis of myocardial cells in AMI, increasing the activity of myocardial cells, and playing a role in alleviating AMI.
Authors
- Meiyu Gu
- Linli Chen (ORCID: https://orcid.org/0000-0001-8685-4792)
- Lu Wang (ORCID: https://orcid.org/0000-0002-7819-2618)
- Zhao Liu (ORCID: https://orcid.org/0000-0003-1734-1824)
- Yongli Luo (ORCID: https://orcid.org/0000-0001-8265-2798)
Institutions
- Zhejiang Chinese Medical University (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-01-01
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00