P692: Impact of sample age on RNA sequencing metrics from FFPE tissues using ion torrent Genexus Integrated Sequencer

RNA fusions have important diagnostic, prognostic, and therapeutic implications in several solid tumor types. Next generation sequencing’s ability to assess a broad range of fusions simultaneously make it ideal for the detection of these fusions and Formalin-fixed paraffin-embedded (FFPE) tissues are the prime specimens for molecular profiling in solid tumors. Given the rapid evolution of tumor RNA profiling, archival FFPE specimens are often pulled and rerun on newer or broader panels in patients with progression of their disease.