P130: The effect of patient uncertainty in family history on genetic testing recommendations for hereditary cancer syndromes

Around 5-10% of cancers are associated with a hereditary cancer syndrome, meaning that patients are born with a germline variant in a specific gene that predisposes them to cancer risk. Those individuals with hereditary risk of developing cancer are offered increased screening and risk reduction options to manage their risk of cancer. For this reason, it is important to identify families with hereditary risk. The National Comprehensive Cancer Network (NCCN) provides criteria based on a patient’s personal and family history of cancer for those who should be offered hereditary cancer testing.

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Publication Details

Journal
Genetics in Medicine Open
Published
2025-01-01
DOI
https://doi.org/10.1016/j.gimo.2025.102974
Primary Topic
BRCA gene mutations in cancer
Type
article
Field-Weighted Citation Impact
0.00
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article

P130: The effect of patient uncertainty in family history on genetic testing recommendations for hereditary cancer syndromes

Tara Maga, Lara Balay, Keith Naylor, Vivian Pan et al.
Genetics in Medicine Open
BRCA gene mutations in cancer
article

P130: The effect of patient uncertainty in family history on genetic testing recommendations for hereditary cancer syndromes

Tara Maga, Lara Balay, Keith Naylor, Vivian Pan, Haley Hultquist, Emma Pappano
article en

Abstract

Around 5-10% of cancers are associated with a hereditary cancer syndrome, meaning that patients are born with a germline variant in a specific gene that predisposes them to cancer risk. Those individuals with hereditary risk of developing cancer are offered increased screening and risk reduction options to manage their risk of cancer. For this reason, it is important to identify families with hereditary risk. The National Comprehensive Cancer Network (NCCN) provides criteria based on a patient’s personal and family history of cancer for those who should be offered hereditary cancer testing.

Genetics in Medicine OpenVol. 3
Illinois College (US), University of Illinois Chicago (US), University of Chicago (US), University of Illinois Hospital & Health Sciences System (US), Community Cancer Center (US)
Good health and well-being
Openalex Percentile: Top 94%
BRCA gene mutations in cancer
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P130: The effect of patient uncertainty in family history on genetic testing recommendations for hereditary cancer syndromes — Tara Maga, Lara Balay, et al. · Genetics in Medicine Open (2025) | TGRS Research Map | TGRS