P130: The effect of patient uncertainty in family history on genetic testing recommendations for hereditary cancer syndromes
Around 5-10% of cancers are associated with a hereditary cancer syndrome, meaning that patients are born with a germline variant in a specific gene that predisposes them to cancer risk. Those individuals with hereditary risk of developing cancer are offered increased screening and risk reduction options to manage their risk of cancer. For this reason, it is important to identify families with hereditary risk. The National Comprehensive Cancer Network (NCCN) provides criteria based on a patient’s personal and family history of cancer for those who should be offered hereditary cancer testing.
Authors
- Tara Maga
- Lara Balay
- Keith Naylor (ORCID: https://orcid.org/0000-0001-9871-8317)
- Vivian Pan (ORCID: https://orcid.org/0000-0002-1666-9273)
- Haley Hultquist
- Emma Pappano
Institutions
- Illinois College (US)
- University of Illinois Chicago (US)
- University of Chicago (US)
- University of Illinois Hospital & Health Sciences System (US)
- Community Cancer Center (US)
Publication Details
- Journal
- Genetics in Medicine Open
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1016/j.gimo.2025.102974
- Primary Topic
- BRCA gene mutations in cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00