Uric Acid Stroke Cerebroprotection Transcended Sex, Age, and Comorbidities in a Multicenter Preclinical Trial
UA provides ischemic stroke cerebroprotection across key relevant biological variables, making it a promising intervention to be further tested in human clinical trials.
Authors
- Raymond C. Koehler (ORCID: https://orcid.org/0000-0002-5890-9992)
- Ivan Budnik (ORCID: https://orcid.org/0000-0002-6652-2667)
- Rakesh B. Patel (ORCID: https://orcid.org/0000-0001-9727-9738)
- Lauren Hachmann Sansing (ORCID: https://orcid.org/0000-0002-6898-1680)
- Jaroslaw Aronowski (ORCID: https://orcid.org/0000-0002-9256-7973)
- Krishnan M. Dhandapani (ORCID: https://orcid.org/0000-0001-7044-1117)
- Yanrong Shi (ORCID: https://orcid.org/0000-0002-3144-5569)
- Jessica Lamb (ORCID: https://orcid.org/0000-0002-0342-9983)
- Louise D. McCullough (ORCID: https://orcid.org/0000-0002-8050-1686)
- Brijesh Sutariya (ORCID: https://orcid.org/0000-0001-8602-0966)
- Anil Kumar Chauhan (ORCID: https://orcid.org/0000-0001-8554-0898)
- Mariia Kumskova (ORCID: https://orcid.org/0000-0002-2477-3011)
- Mohammad Badruzzaman Khan (ORCID: https://orcid.org/0000-0001-8231-1256)
- Cenk Ayata (ORCID: https://orcid.org/0000-0002-3644-6042)
- Pradip Kumar Kamat (ORCID: https://orcid.org/0000-0002-0376-2284)
- Daniel R. Thedens (ORCID: https://orcid.org/0000-0002-4704-3185)
- David Charles Hess (ORCID: https://orcid.org/0000-0002-8345-9153)
- Xuyan Jin (ORCID: https://orcid.org/0009-0003-1923-4923)
- Márcio A. Diniz (ORCID: https://orcid.org/0000-0002-2427-7843)
- Karisma A. Nagarkatti (ORCID: https://orcid.org/0000-0002-7300-9968)
- В. А. Кузнецов (ORCID: https://orcid.org/0000-0002-3046-0724)
- Enrique C. C Leira (ORCID: https://orcid.org/0000-0003-3695-2946)
- Lígia Simões Braga Boisserand (ORCID: https://orcid.org/0000-0002-0058-2894)
- Anna M. Planas (ORCID: https://orcid.org/0000-0002-6147-1880)
- Takahiko Imai (ORCID: https://orcid.org/0000-0002-4422-2946)
- Nirav Dhanesha (ORCID: https://orcid.org/0000-0001-9268-4363)
- Hanish Kodali (ORCID: https://orcid.org/0000-0002-8229-4369)
- Patrick D. Lyden (ORCID: https://orcid.org/0000-0001-6170-4042)
- Basavaraju G. Sanganahalli (ORCID: https://orcid.org/0000-0002-0851-6621)
- Brooklyn D. Avery (ORCID: https://orcid.org/0009-0009-7093-7580)
- Abhishek Jha (ORCID: https://orcid.org/0000-0001-9229-0612)
- Anjali Chauhan (ORCID: https://orcid.org/0000-0002-9825-8100)
- Ángel Chamorro (ORCID: https://orcid.org/0000-0002-0392-6285)
- Aditi Jain (ORCID: https://orcid.org/0000-0003-2237-3249)
Institutions
- University of Southern California (US)
- University of Iowa (US)
- Johns Hopkins University (US)
- Augusta University (US)
- Johns Hopkins Medicine (US)
- Yale University (US)
- Jacksonville University (US)
- Massachusetts General Hospital (US)
- Hospital Clínic de Barcelona (ES)
- Institut d'Investigacions Biomèdiques de Barcelona (ES)
- National Research Council (LK)
- The University of Texas Health Science Center (US)
- Consorci Institut D'Investigacions Biomediques August Pi I Sunyer (ES)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- Stroke
- Published
- 2025-03-17
- DOI
- https://doi.org/10.1161/strokeaha.124.048748
- Citations
- 10
- Primary Topic
- Acute Ischemic Stroke Management
- Type
- article
- Field-Weighted Citation Impact
- 13.54