Formulation & Testing 0f Physicochemical Properties of Indigenously Made Phytic Acid Incorporated Glass Ionomer Cement – “An In Vitro Study”

Background: Phytic acid (IP6), also known as myo-inositol hexaphosphate, is a naturally abundant compound, particularly prevalent in plants, It is present in edible cereals, legumes, nuts, oilseeds, and tubers.IP6 is a promising compound with potential applications across various fields of dentistry, including endodontics, restorative dentistry, and implantology. Aim: The aim of the study is to formulate & evaluate the physicochemical properties of Ip6 incorporated Glass Ionomer cement. Materials and Methods: Phytic acid (Ip6) liquid was prepared at 1%, 2%,5% concentrations, followed by the addition of these modified liquids at various concentrations into conventional GIC liquid. A total of 80 specimens were prepared by mixing modified liquids of various concentrations into conventional GIC powder. The specimens were grouped into four types based on the modified liquids used which is as follows Group 1 is conventional GIC, Groups 2, 3, and 4 included 1%, 2%, and 5% phytic acid incorporated GIC respectively. The compressive strength of the specimens were assessed using a universal testing machine. Results: The results of the study showed a statistically significant increase in compressive strength with a mean value of (56.40 + 29.63 MPa) in 5% incorporated GIC, followed by 2% incorporated GIC (40.83 + 19.54 MPa )and 1% showed the lowest compressive strength (25.69+11.64 MPa). Conclusion: Phytic acid incorporation into Glass Ionomer Cement (GIC) is a game-changer, significantly boosting its compressive strength, especially at higher concentrations of 5%. This innovative enhancement transforms GIC into a more robust and durable restorative material while harnessing the unique benefits of IP6, including biocompatibility, antioxidant, and cariostatic properties.

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Publication Details

Journal
Journal of Neonatal Surgery
Published
2025-03-11
DOI
https://doi.org/10.52783/jns.v14.2049
Primary Topic
Oral and gingival health research
Type
article
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article

Formulation & Testing 0f Physicochemical Properties of Indigenously Made Phytic Acid Incorporated Glass Ionomer Cement – “An In Vitro Study”

Pradeep Mishra, Shilpi Tiwari, Ashok Menon, Parimala Kulkarni et al.
Journal of Neonatal Surgery
Oral and gingival health research
article

Formulation & Testing 0f Physicochemical Properties of Indigenously Made Phytic Acid Incorporated Glass Ionomer Cement – “An In Vitro Study”

Pradeep Mishra, Shilpi Tiwari, Ashok Menon, Parimala Kulkarni, Shikha Mali, Poonam Malani
article en

Abstract

Background: Phytic acid (IP6), also known as myo-inositol hexaphosphate, is a naturally abundant compound, particularly prevalent in plants, It is present in edible cereals, legumes, nuts, oilseeds, and tubers.IP6 is a promising compound with potential applications across various fields of dentistry, including endodontics, restorative dentistry, and implantology. Aim: The aim of the study is to formulate & evaluate the physicochemical properties of Ip6 incorporated Glass Ionomer cement. Materials and Methods: Phytic acid (Ip6) liquid was prepared at 1%, 2%,5% concentrations, followed by the addition of these modified liquids at various concentrations into conventional GIC liquid. A total of 80 specimens were prepared by mixing modified liquids of various concentrations into conventional GIC powder. The specimens were grouped into four types based on the modified liquids used which is as follows Group 1 is conventional GIC, Groups 2, 3, and 4 included 1%, 2%, and 5% phytic acid incorporated GIC respectively. The compressive strength of the specimens were assessed using a universal testing machine. Results: The results of the study showed a statistically significant increase in compressive strength with a mean value of (56.40 + 29.63 MPa) in 5% incorporated GIC, followed by 2% incorporated GIC (40.83 + 19.54 MPa )and 1% showed the lowest compressive strength (25.69+11.64 MPa). Conclusion: Phytic acid incorporation into Glass Ionomer Cement (GIC) is a game-changer, significantly boosting its compressive strength, especially at higher concentrations of 5%. This innovative enhancement transforms GIC into a more robust and durable restorative material while harnessing the unique benefits of IP6, including biocompatibility, antioxidant, and cariostatic properties.

Journal of Neonatal SurgeryVol. 14(5S)
Openalex Percentile: Top 92%
Oral and gingival health research
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Formulation & Testing 0f Physicochemical Properties of Indigenously Made Phytic Acid Incorporated Glass Ionomer Cement – “An In Vitro Study” — Pradeep Mishra, Shilpi Tiwari, et al. · Journal of Neonatal Surgery (2025) | TGRS Research Map | TGRS