Review of plants as a promising source of bioactive peptides for the treatment of diabetes
Abstract The bioactive compounds found in plants offer numerous therapeutic properties through protein and peptide molecules. The occurrence of diabetes has developed into a significant worldwide healthcare crisis because this metabolic disease continues to affect millions of individuals throughout the world while growing in numbers annually. The uncontrolled nature of diabetes produces serious complications which include microangiopathy together with ketoacidosis followed by cardiovascular diseases. Drugs used in diabetes treatment exist yet their marketplace costs combined with side effects make researchers seek new therapeutic techniques. The use of bioactive peptides extracted from plants attracts researchers because they show proven ability to regulate diabetes-related metabolic pathways through insulin sensitivity enhancement and blood glucose control along with weight management activities, anti-inflammatory processes, and antioxidant properties. This review investigates plant-derived bioactive peptides with antidiabetic potential through detailed research on their biological mechanisms. current developments in their screening process, and their potential uses in killing diabetes through new treatment methods.
Authors
- Debajyoti Bose (ORCID: https://orcid.org/0000-0002-3457-6994)
- Riya Bhattacharya (ORCID: https://orcid.org/0000-0001-9175-2256)
- Fareeha Nadeem
- Quratulain Maqsood (ORCID: https://orcid.org/0000-0001-7342-9797)
- Tahir Mehmood (ORCID: https://orcid.org/0000-0002-7354-328X)
- Kushif Meer
- Hajra Ashraf
- Bisma Meer
Institutions
- Quaid-i-Azam University (PK)
- University of the Punjab (PK)
- Woxsen School of Business (IN)
- University of Veterinary and Animal Sciences (PK)
Publication Details
- Journal
- CABI Reviews
- Published
- 2025-03-17
- DOI
- https://doi.org/10.1079/cabireviews.2025.0018
- Primary Topic
- Protein Hydrolysis and Bioactive Peptides
- Type
- article
- Field-Weighted Citation Impact
- 0.00