National Consensus Guideline on Diagnosis and Management of Chronic Granulomatous Disease

Currently, a national consensus or guideline for diagnosing and managing patients suspected of having chronic granulomatous disease (CGD) is lacking. This consensus is written based on a combination of scien- tific literature and comments from the expert panel of Iranian immunologists. A group of clinical immunol- ogists reviewed the current consensus, presented their comments at a meeting titled “First Meeting on the Diagnosis of Inborn Errors of Immunity (IEI) by IEI Experts” and agreed on this consensus. This consensus guideline provides recommendations on the diagnosis, antimicrobial prophylaxis, management of clinical manifestations, administration of interferon gamma (IFN-γ) and hematopoietic stem cell transplantation (HSCT) for patients with CGD.

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Journal
Immunology and Genetics Journal
Published
2025-03-16
DOI
https://doi.org/10.18502/igj.v8i3.18170
Primary Topic
Neutrophil, Myeloperoxidase and Oxidative Mechanisms
Type
article
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National Consensus Guideline on Diagnosis and Management of Chronic Granulomatous Disease

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National Consensus Guideline on Diagnosis and Management of Chronic Granulomatous Disease

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article en

Abstract

Currently, a national consensus or guideline for diagnosing and managing patients suspected of having chronic granulomatous disease (CGD) is lacking. This consensus is written based on a combination of scien- tific literature and comments from the expert panel of Iranian immunologists. A group of clinical immunol- ogists reviewed the current consensus, presented their comments at a meeting titled “First Meeting on the Diagnosis of Inborn Errors of Immunity (IEI) by IEI Experts” and agreed on this consensus. This consensus guideline provides recommendations on the diagnosis, antimicrobial prophylaxis, management of clinical manifestations, administration of interferon gamma (IFN-γ) and hematopoietic stem cell transplantation (HSCT) for patients with CGD.

Immunology and Genetics Journal
Isfahan University of Medical Sciences (IR), Ahvaz Jundishapur University of Medical Sciences (IR), Iran University of Medical Sciences (IR), Tabriz University of Medical Sciences (IR), Mashhad University of Medical Sciences (IR), Shiraz University of Medical Sciences (IR), Guilan University of Medical Sciences (IR), University of Tehran (IR), New York State Department of Labor (US), Islamic Azad University Medical Branch of Tehran (IR), Masih Daneshvari Hospital (IR), Rasool Akram Hospital (IR), Children's Medical Center (IR), Stem Cell Technology Research Center (IR), North Khorasan University of Medical Sciences (IR), Shahid Beheshti University of Medical Sciences (IR), Tehran University of Medical Sciences (IR)
Openalex Percentile: Top 95%
Neutrophil, Myeloperoxidase and Oxidative Mechanisms
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