A Study of Immunohistochemical Expression of p63 in Colorectal Carcinoma
Moderate-to-strong cytoplasmic p63 expression was seen only in malignancy, suggesting its role in carcinogenesis. Increased p63 staining intensity from low- to high-grade tumours indicates p63 as a marker of poor differentiation. The correlation between metastasis and stronger p63 expression with higher TNM/AJCC stages confirms elevated p63 in aggressive tumours.
Authors
- Sai Sudha Muddha (ORCID: https://orcid.org/0000-0003-2433-7436)
- Thanka Johnson (ORCID: https://orcid.org/0000-0002-7499-5552)
- Aishwarya Prasad Nair
Institutions
- Sree Balaji Dental College and Hospital (IN)
Publication Details
- Journal
- Nigerian Postgraduate Medical Journal
- Published
- 2025-01-01
- DOI
- https://doi.org/10.4103/npmj.npmj_297_24
- Primary Topic
- Cancer-related Molecular Pathways
- Type
- article
- Field-Weighted Citation Impact
- 0.00