Patient with recurrent grade 4 astrocytoma responding favorably to intranasal delivery of NEO100, highly pure perillyl alcohol: illustrative case

The authors present a case in which IN cancer therapy with NEO100 was well tolerated and was associated with striking tumor regression, providing further evidence that this novel conceptual approach to cancer therapy might become useful for the improved treatment of recurrent glioma. https://thejns.org/doi/10.3171/CASE24683.

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Publication Details

Journal
Journal of Neurosurgery Case Lessons
Published
2025-03-17
DOI
https://doi.org/10.3171/case24683
Primary Topic
Glioma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
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article

Patient with recurrent grade 4 astrocytoma responding favorably to intranasal delivery of NEO100, highly pure perillyl alcohol: illustrative case

Axel H. Schönthal, Rhonda Mittenzwei, Frank M. Senecal, Thomas C. Chen et al.
Journal of Neurosurgery Case Lessons
Glioma Diagnosis and Treatment
article

Patient with recurrent grade 4 astrocytoma responding favorably to intranasal delivery of NEO100, highly pure perillyl alcohol: illustrative case

Axel H. Schönthal, Rhonda Mittenzwei, Frank M. Senecal, Thomas C. Chen, Stephen Swenson, John L. Go
article en

Abstract

The authors present a case in which IN cancer therapy with NEO100 was well tolerated and was associated with striking tumor regression, providing further evidence that this novel conceptual approach to cancer therapy might become useful for the improved treatment of recurrent glioma. https://thejns.org/doi/10.3171/CASE24683.

Journal of Neurosurgery Case LessonsVol. 9(11)
University of Southern California (US), University of California, Los Angeles (US), University of Washington (US), USC Norris Comprehensive Cancer Center (US), King County Medical Examiner's Office (US), Northwest Medical Specialties (US), Neurological Surgery (US)
Good health and well-being
Openalex Percentile: Top 93%
Glioma Diagnosis and Treatment
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Patient with recurrent grade 4 astrocytoma responding favorably to intranasal delivery of NEO100, highly pure perillyl alcohol: illustrative case — Axel H. Schönthal, Rhonda Mittenzwei, et al. · Journal of Neurosurgery Case Lessons (2025) | TGRS Research Map | TGRS