Diagnostic Efficacy and Clinical Significance of Lymphocyte Subsets, Granzyme B and Perforin in the Peripheral Blood of Patients with Invasive Breast Cancer Following Neoadjuvant Chemotherapy
These findings indicated that peripheral blood lymphocyte subsets, along with granzyme B and perforin levels, could serve as potential biomarkers for differentiating benign from malignant breast tumors, assessing anti-tumor immunity and predicting chemotherapy efficacy.
Authors
- Minggui Chen
- Yuluo Wu
- Zhaowei Zhuang
- Han Liu (ORCID: https://orcid.org/0009-0005-5883-6278)
- Ruinian Zheng
- Yan Zeng (ORCID: https://orcid.org/0009-0005-6239-5049)
- Liwen Xue
Institutions
- Central People's Hospital of Zhanjiang (CN)
- Dongguan People’s Hospital (CN)
Publication Details
- Journal
- Cancer Management and Research
- Published
- 2025-03-01
- DOI
- https://doi.org/10.2147/cmar.s502155
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Basic and Applied Basic Research Foundation of Guangdong Province