Giant Uterine Tumor Compatible With Sarcoma

Uterine sarcomas are a heterogeneous group of very rare tumors of mesenchymal origin, accounting for approximately 4% of malignant tumors of the uterus. These represent a heterogeneous group of neoplasms that are classified by histology in order of frequency as leiomyosarcoma, endometrial stromal sarcoma, and carcinosarcoma or mixed mullerian tumor. Even in its early stages, uterine sarcoma has a bad prognosis and is a very rare disease that is difficult to identify and typically detected by anatomopathological studies. They are a type of cancer derived from the mesenchyme or connective tissue of the uterus that have a wide variety of histological aspects and biological activity, which makes their classification difficult. A 78-year-old woman reported experiencing abdominal pain, adynamia, and asthenia along with an increase in abdominal volume about six months ago. A physical examination revealed this increase, and a surgical procedure involving radical hysterectomy with peritoneal implants and pelvic lymph node dissection was chosen. The patient was transferred to the intensive care unit due to hypovolemic shock secondary to abdominal decompression and intraoperative hemorrhage, with a surgical product of 6.115 kilos. The patient had an adequate clinical evolution and was discharged one week later from the hospital for adjuvant treatment with chemotherapy and radiotherapy. However, after three weeks of follow-up, she died due to disease progression. Treatment recommendations for patients with uterine sarcoma are based on the results of retrospective studies, which makes clinical management difficult.

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Publication Details

Journal
Cureus
Published
2025-03-05
DOI
https://doi.org/10.7759/cureus.80101
Primary Topic
Uterine Myomas and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Giant Uterine Tumor Compatible With Sarcoma

F. Javier Rodríguez‐Rajo, Alfredo Saad Ganem, Lizette Gil, Adriana Margarita Acosta Blanco et al.
Cureus
Uterine Myomas and Treatments
article

Giant Uterine Tumor Compatible With Sarcoma

F. Javier Rodríguez‐Rajo, Alfredo Saad Ganem, Lizette Gil, Adriana Margarita Acosta Blanco, Elias Gallardo-Navarro
article en

Abstract

Uterine sarcomas are a heterogeneous group of very rare tumors of mesenchymal origin, accounting for approximately 4% of malignant tumors of the uterus. These represent a heterogeneous group of neoplasms that are classified by histology in order of frequency as leiomyosarcoma, endometrial stromal sarcoma, and carcinosarcoma or mixed mullerian tumor. Even in its early stages, uterine sarcoma has a bad prognosis and is a very rare disease that is difficult to identify and typically detected by anatomopathological studies. They are a type of cancer derived from the mesenchyme or connective tissue of the uterus that have a wide variety of histological aspects and biological activity, which makes their classification difficult. A 78-year-old woman reported experiencing abdominal pain, adynamia, and asthenia along with an increase in abdominal volume about six months ago. A physical examination revealed this increase, and a surgical procedure involving radical hysterectomy with peritoneal implants and pelvic lymph node dissection was chosen. The patient was transferred to the intensive care unit due to hypovolemic shock secondary to abdominal decompression and intraoperative hemorrhage, with a surgical product of 6.115 kilos. The patient had an adequate clinical evolution and was discharged one week later from the hospital for adjuvant treatment with chemotherapy and radiotherapy. However, after three weeks of follow-up, she died due to disease progression. Treatment recommendations for patients with uterine sarcoma are based on the results of retrospective studies, which makes clinical management difficult.

CureusVol. 17(3)
Hospital Español (MX)
Good health and well-being
Openalex Percentile: Top 93%
Uterine Myomas and Treatments
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