Associations between RetNet gene polymorphisms and the efficacy of orthokeratology for myopia control: a retrospective clinical study
The effectiveness of orthokeratology lens treatment relates to interindividual variability in the control of AL growth in myopic eyes. The efficacy increased when patients carried more nonsynonymous variants in retinal disease-related gene sets. These data serve as reference for genetic counselling and the management of patients who choose orthokeratology lenses to control myopia.
Authors
- Xinjie Mao (ORCID: https://orcid.org/0000-0001-9446-548X)
- Shilai Xing (ORCID: https://orcid.org/0000-0002-0869-1120)
- Xiangyi Yu
- Ruijing Xia
- Fan Lü (ORCID: https://orcid.org/0000-0003-0846-147X)
- Xiaoguang Yu
- Hao Wu (ORCID: https://orcid.org/0000-0001-8448-5284)
- Lulu Peng (ORCID: https://orcid.org/0000-0002-2318-5955)
- Zhenlin Du
Institutions
- Wenzhou Medical University (CN)
- Affiliated Eye Hospital of Wenzhou Medical College (CN)
- ID Genomics (United States) (US)
- Sinotech Genomics (China) (CN)
Publication Details
- Journal
- Eye and Vision
- Published
- 2025-03-17
- DOI
- https://doi.org/10.1186/s40662-025-00426-4
- Citations
- 2
- Primary Topic
- Ophthalmology and Visual Impairment Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.71