Enhanced Tear Film Concentrations of Cefazolin and Chloramphenicol Using Cross‐Linked Hyaluronic Acid in Canine Eyes
The cross-linked hyaluronic acid significantly enhanced the retention and overall exposure of both cefazolin and chloramphenicol in the canine tear film. These findings suggest that XHA could serve as a superior delivery vehicle for ocular antibiotics, potentially improving treatment outcomes for ophthalmic infections.
Authors
- Ron Ofri (ORCID: https://orcid.org/0000-0002-3825-3113)
- Dikla Arad (ORCID: https://orcid.org/0000-0001-7084-897X)
- Lionel Sebbag (ORCID: https://orcid.org/0000-0002-0103-0127)
- Eli Mordechai
- Yulia Goncharov
Institutions
- Hebrew University of Jerusalem (IL)
Publication Details
- Journal
- Veterinary Ophthalmology
- Published
- 2025-03-16
- DOI
- https://doi.org/10.1111/vop.70013
- Citations
- 1
- Primary Topic
- Ocular Surface and Contact Lens
- Type
- article
- Field-Weighted Citation Impact
- 1.88