Dissecting the causal association of periodontitis with biological aging and its underlying mechanisms: findings from Mendelian randomization and integrative genetic analysis
This study presents compelling genetic evidence supporting a causal relationship between periodontitis and accelerated aging. Further research is required to validate these findings and investigate the underlying mechanisms.
Authors
- Lijian Jin (ORCID: https://orcid.org/0000-0002-5340-9710)
- Ke Deng (ORCID: https://orcid.org/0000-0003-1308-0399)
- Shixian Hu (ORCID: https://orcid.org/0000-0002-1190-0325)
- Zuyun Liu (ORCID: https://orcid.org/0000-0001-6120-5913)
- Mi Du (ORCID: https://orcid.org/0000-0002-2237-9918)
- Yu Cao (ORCID: https://orcid.org/0000-0003-1409-2068)
- George Pelekos (ORCID: https://orcid.org/0000-0003-1917-1988)
- Li An (ORCID: https://orcid.org/0000-0002-7933-5174)
Institutions
- Shandong University (CN)
- Sun Yat-sen University (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
- Second Affiliated Hospital of Zhejiang University (CN)
- Southern Medical University (CN)
- University of Hong Kong (HK)
Publication Details
- Journal
- Journal of Periodontal & Implant Science
- Published
- 2025-01-01
- DOI
- https://doi.org/10.5051/jpis.2403420171
- Citations
- 1
- Primary Topic
- Digestive system and related health
- Type
- article
- Field-Weighted Citation Impact
- 1.82
Funders
- University of Hong Kong
- National Institute on Alcohol Abuse and Alcoholism