Multi-omics analysis identifies OSGEPL1 as an oncogene in hepatocellular carcinoma
This study implicates t<sup>6</sup>A modification pathway dysregulation in HCC prognosis, identifying OSGEPL1 as a potential therapeutic target. These findings provide novel insights into HCC pathogenesis and may guide future treatment strategies.
Authors
- Kai Wen (ORCID: https://orcid.org/0000-0002-4039-4353)
- Sintim Mui (ORCID: https://orcid.org/0000-0001-9254-2330)
- Zhiyu Xiao (ORCID: https://orcid.org/0000-0003-0746-7116)
- Yongcong Yan (ORCID: https://orcid.org/0000-0002-7269-764X)
- Juanyi Shi (ORCID: https://orcid.org/0009-0005-3967-0129)
- Huoming Li (ORCID: https://orcid.org/0009-0007-0799-4043)
- Weidong Wang (ORCID: https://orcid.org/0000-0003-2523-3145)
- Zhenyu Zhou (ORCID: https://orcid.org/0000-0003-0585-8703)
Institutions
- Sun Yat-sen University (CN)
- Sun Yat-sen Memorial Hospital (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-03-16
- DOI
- https://doi.org/10.1007/s12672-025-02066-5
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Beijing Xisike Clinical Oncology Research Foundation
- National Natural Science Foundation of China
- Basic and Applied Basic Research Foundation of Guangdong Province