Bioinformatics identification and validation of pyroptosis-related gene for ischemic stroke
Our finding indicated that Irf1, Icam1, Tlr2, Cebpb, and Il1rn are hub genes associated with pyroptosis, and these genes are all associated with different immune cells, so as to provide new targets for the prevention and treatment of IS from the perspective of pyroptosis.
Authors
- Xinying Shang
- Rui-Li Wei (ORCID: https://orcid.org/0000-0003-2696-6586)
- Bo Yu (ORCID: https://orcid.org/0000-0002-5579-6806)
- Di Yang
- Wei Zhang (ORCID: https://orcid.org/0000-0002-4375-0368)
Institutions
- Kunming Medical University (CN)
- First Affiliated Hospital of Kunming Medical University (CN)
Publication Details
- Journal
- BMC Medical Genomics
- Published
- 2025-03-16
- DOI
- https://doi.org/10.1186/s12920-025-02119-2
- Citations
- 2
- Primary Topic
- Inflammasome and immune disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- National Natural Science Foundation of China
- Applied Basic Research Foundation of Yunnan Province