Isolated Suprasellar Chordoma Mimicking Pituitary Adenoma: A Case Report

Chordomas are uncommon neoplasms predominantly observed in adult males, typically middle-aged. These tumors present with diverse clinical features, including headaches, cranial neuropathies, and cerebrospinal fluid leakage. Surgical intervention is often complex due to tumor location or postresection reconstruction requirements, necessitating a multidisciplinary approach for optimal management. The report describes an atypical case of a 20-year-old female patient presenting with persistent headaches and visual disturbances. Magnetic resonance imaging (MRI) revealed a large sellar/suprasellar mass initially suggestive of a pituitary adenoma. Following surgical excision, histopathological analysis confirmed a chordoma. This report emphasizes the diagnostic and therapeutic challenges of suprasellar chordomas, which may radiologically mimic common sellar lesions. The case underscores the importance of including chordoma in the differential diagnosis of sellar/suprasellar masses, especially in younger patients with visual impairment and headache.

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Publication Details

Journal
Cureus
Published
2025-03-16
DOI
https://doi.org/10.7759/cureus.80647
Primary Topic
Bone Tumor Diagnosis and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Isolated Suprasellar Chordoma Mimicking Pituitary Adenoma: A Case Report

Nawaf Alghamdi, Fahad Albadr, Mohammed K Al-Quwayee, Rayan N Almasoud et al.
Cureus
Bone Tumor Diagnosis and Treatments
article

Isolated Suprasellar Chordoma Mimicking Pituitary Adenoma: A Case Report

Nawaf Alghamdi, Fahad Albadr, Mohammed K Al-Quwayee, Rayan N Almasoud, Zeyad Abdulrahman Alhathloul, Mohamed Alquhidan
article en

Abstract

Chordomas are uncommon neoplasms predominantly observed in adult males, typically middle-aged. These tumors present with diverse clinical features, including headaches, cranial neuropathies, and cerebrospinal fluid leakage. Surgical intervention is often complex due to tumor location or postresection reconstruction requirements, necessitating a multidisciplinary approach for optimal management. The report describes an atypical case of a 20-year-old female patient presenting with persistent headaches and visual disturbances. Magnetic resonance imaging (MRI) revealed a large sellar/suprasellar mass initially suggestive of a pituitary adenoma. Following surgical excision, histopathological analysis confirmed a chordoma. This report emphasizes the diagnostic and therapeutic challenges of suprasellar chordomas, which may radiologically mimic common sellar lesions. The case underscores the importance of including chordoma in the differential diagnosis of sellar/suprasellar masses, especially in younger patients with visual impairment and headache.

CureusVol. 17(3)
King Saud University (SA)
Zero hunger
Openalex Percentile: Top 93%
Bone Tumor Diagnosis and Treatments
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