Investigating the impact of multidimensional sleep traits on cardiovascular diseases and the mediating role of depression
Our study provides evidence that genetically predicted insomnia, short sleep, frequent daytime napping and sleepiness are associated with a higher risk of certain CVD subtypes, partly mediated by MDD.
Authors
- Xiuwen Li (ORCID: https://orcid.org/0000-0002-1076-2899)
- Hao Zhao (ORCID: https://orcid.org/0000-0002-8879-9595)
- Roger S. McIntyre (ORCID: https://orcid.org/0000-0003-4733-2523)
- Kayla M. Teopiz (ORCID: https://orcid.org/0000-0001-8429-6563)
- Lan Guo
- Xiaojie Wang (ORCID: https://orcid.org/0000-0001-5570-6121)
- Ciyong Lu (ORCID: https://orcid.org/0000-0003-4266-4967)
- Wanxin Wang (ORCID: https://orcid.org/0000-0003-4979-9514)
Institutions
- University Health Network (CA)
- Sun Yat-sen University (CN)
- University of Toronto (CA)
- ShenZhen People’s Hospital (CN)
Publication Details
- Journal
- Open Heart
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1136/openhrt-2024-002866
- Citations
- 2
- Primary Topic
- Sleep and related disorders
- Type
- article
- Field-Weighted Citation Impact
- 4.24
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Guangdong Province