Effect of Postconditioning With Intralipid in Patients Undergoing Off-Pump Coronary Artery Bypass Surgery: A Randomized Controlled Trial

As evidenced by comparable postoperative cardiac enzyme levels between the intralipid and control groups, we did not find a postconditioning role of IL in OPCAB surgery, suggesting that IL may not provide cardioprotection in this setting. The authors propose a further investigation into alternative administration protocols (like varying doses and administration timings of IL) to elucidate its potential impact as a postconditioning agent in OPCAB.

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Publication Details

Journal
Cureus
Published
2025-03-14
DOI
https://doi.org/10.7759/cureus.80593
Primary Topic
Cardiac Ischemia and Reperfusion
Type
article
Field-Weighted Citation Impact
0.00
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article

Effect of Postconditioning With Intralipid in Patients Undergoing Off-Pump Coronary Artery Bypass Surgery: A Randomized Controlled Trial

Gegal Pruthi, Anju Grewal, Praveen Choudhary, P S Nagraj et al.
Cureus
Cardiac Ischemia and Reperfusion
article

Effect of Postconditioning With Intralipid in Patients Undergoing Off-Pump Coronary Artery Bypass Surgery: A Randomized Controlled Trial

Gegal Pruthi, Anju Grewal, Praveen Choudhary, P S Nagraj, Hemanthkumar Tamilchelvan, Rajiv Kumar, NaveenG Singh
article en

Abstract

As evidenced by comparable postoperative cardiac enzyme levels between the intralipid and control groups, we did not find a postconditioning role of IL in OPCAB surgery, suggesting that IL may not provide cardioprotection in this setting. The authors propose a further investigation into alternative administration protocols (like varying doses and administration timings of IL) to elucidate its potential impact as a postconditioning agent in OPCAB.

CureusVol. 17(3)
Sri Jayadeva Institute of Cardiovascular Sciences and Research (IN), All India Institute of Medical Sciences (IN)
Good health and well-being
Openalex Percentile: Top 93%
Cardiac Ischemia and Reperfusion
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