Durability of antibody titers and associated factors after the booster dose of <scp>COVID</scp>‐19 <scp>mRNA</scp> vaccination in <scp>Japanese SARS</scp>‐<scp>CoV</scp>‐2 infection‐naive residents in geriatric intermediate care facilities
The third dose of mRNA vaccine boosted the immune response of elderly residents. However, their antibody titers, particularly in steroid users, were highly attenuated 6 months after the last vaccination. For this population, attention should be focused on additional vaccinations. Geriatr Gerontol Int 2025; 25: 588-597.
Authors
- Yoshiko Yodoi
- Yasutoshi Kido (ORCID: https://orcid.org/0000-0003-3615-2631)
- Ayako Konishi (ORCID: https://orcid.org/0000-0002-8135-055X)
- Kazuhiro Matsumoto (ORCID: https://orcid.org/0000-0001-9222-0999)
- Akifumi Deguchi
- Tomoka Matsuura (ORCID: https://orcid.org/0000-0002-0127-7146)
- Ayane Kasamatsu (ORCID: https://orcid.org/0000-0002-5263-0835)
- Noboru Sakamoto (ORCID: https://orcid.org/0000-0002-4684-0297)
- Yu Nakagama (ORCID: https://orcid.org/0000-0001-9780-9719)
- Asae Suita (ORCID: https://orcid.org/0000-0002-2755-4447)
- Satoko Ohfuji (ORCID: https://orcid.org/0000-0003-3239-5249)
- Tetsuo Kase (ORCID: https://orcid.org/0000-0001-5638-3803)
- Hiroshi Kakeya (ORCID: https://orcid.org/0000-0002-6251-1696)
- Emiko Mukai (ORCID: https://orcid.org/0000-0002-5554-1803)
- Mikio Fujimoto (ORCID: https://orcid.org/0000-0002-9399-124X)
- Kaori Iwasaka
- Kazuko Iba
- Wakaba Fukushima (ORCID: https://orcid.org/0000-0002-3666-6942)
- Yoshio Hirota (ORCID: https://orcid.org/0000-0001-5406-3240)
- Hikaru Sakamoto
- Tetsuya Kita
- Kyoko Kondo
- Hideki Sakamoto
- H. Nakata
Institutions
- Osaka City University (JP)
- Koujin Hospital (JP)
- SOUSEIKAI Global Clinical Research Center (JP)
- Osaka Hospital (JP)
- Osaka Metropolitan University (JP)
- Osaka International University (JP)
- Tokyo Metropolitan University (JP)
Publication Details
- Journal
- Geriatrics and gerontology international/Geriatrics & gerontology international
- Published
- 2025-03-15
- DOI
- https://doi.org/10.1111/ggi.70028
- Primary Topic
- SARS-CoV-2 and COVID-19 Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00