Unilateral schizencephaly open lip with septo optic dysplasia in adult woman with glaucoma: A rare case

This case report presents a 38-year-old female with unilateral open-lip schizencephaly coexisting with septo-optic dysplasia. The patient lacked motor deficits, maintaining normal developmental milestones. schizencephaly is a rare cortical malformation characterized presence of abnormal cleft in the cerebral hemispheres of the brain. These clefts extend from the surface of the brain to the ventricles. Lissencephaly can be unilateral and bilateral and divided into open lips and closed lip. It is frequently associated with other anomaly such as septo-optic dysplasia, grey matter heterotopia, septum pellucidum, and dysgenesis of the corpus callosum. Schizencephaly has no known gender predilection, and estimated incidence of 1.5: 100,000 live birth. Radiological imaging is the cornerstone of diagnosis schizencephaly.