Assessing changes on large cerebral arteries in CADASIL: Preliminary insights from a case-control analysis
Traditionally considered a small-vessel disease, patients with CADASIL have larger BA diameters and possibly higher cervical ICA tortuosity than controls. Whether these changes are part of the NOTCH-3 mutation phenotype or influence the clinical course is uncertain but should be further investigated.
Authors
- Kursat Gurel (ORCID: https://orcid.org/0000-0003-1484-803X)
- Jane S. Paulsen (ORCID: https://orcid.org/0000-0002-0983-228X)
- Antonio Spagnolo‐Allende (ORCID: https://orcid.org/0000-0001-6057-4469)
- Khrystyna Kozii (ORCID: https://orcid.org/0009-0004-9889-1493)
- José Gutierrez (ORCID: https://orcid.org/0000-0002-2175-8078)
- Salwa Rahman (ORCID: https://orcid.org/0000-0002-2123-3845)
- Farid Khasiyev (ORCID: https://orcid.org/0000-0002-3127-0973)
- Edgar R. Lopez-Navarro (ORCID: https://orcid.org/0000-0001-9237-9000)
- Kevin Strobino
- Brenno R. Barreto
- Pedro G Bueno
- Silvia Mayer
Institutions
- Albert Einstein College of Medicine (US)
- State University of New York (US)
- NewYork–Presbyterian Hospital (US)
- University of Wisconsin–Madison (US)
- University of Miami (US)
- Medical University of South Carolina (US)
- Columbia University Irving Medical Center (US)
- Trinity Health Oakland Hospital (US)
Publication Details
- Journal
- Journal of Stroke and Cerebrovascular Diseases
- Published
- 2025-03-15
- DOI
- https://doi.org/10.1016/j.jstrokecerebrovasdis.2025.108294
- Citations
- 1
- Primary Topic
- Cerebrovascular and genetic disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- National Institutes of Health
- National Institute on Aging