A Rare TPM3-NTRK1 fusion in a fetal pelvic mass

Early recognition and characterization of soft tissue tumors is important for proper fetal and maternal care. Here, we present sonographic, fetal and postnatal MRI, and pathological findings of a rare case of congenital NTRK-rearranged malignant spindle cell sarcoma with TPM3-NTRK1 fusion in a male fetus.

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Publication Details

Journal
Radiology Case Reports
Published
2025-03-15
DOI
https://doi.org/10.1016/j.radcr.2025.02.079
Primary Topic
Neuroblastoma Research and Treatments
Type
article
Field-Weighted Citation Impact
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article

A Rare TPM3-NTRK1 fusion in a fetal pelvic mass

J Kucera, Lei Shao, Maryam Kazelka, Michael Mcgraw
Radiology Case Reports
Neuroblastoma Research and Treatments
article

A Rare TPM3-NTRK1 fusion in a fetal pelvic mass

J Kucera, Lei Shao, Maryam Kazelka, Michael Mcgraw
article en

Abstract

Early recognition and characterization of soft tissue tumors is important for proper fetal and maternal care. Here, we present sonographic, fetal and postnatal MRI, and pathological findings of a rare case of congenital NTRK-rearranged malignant spindle cell sarcoma with TPM3-NTRK1 fusion in a male fetus.

Radiology Case ReportsVol. 20(6)
University of Central Florida (US), University of South Florida (US), Tampa General Hospital (US), Nemours Children's Clinic (US)
Zero hunger
Openalex Percentile: Top 92%
Neuroblastoma Research and Treatments
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