T-cell branched glycosylation as a mediator of colitis-associated colorectal cancer progression: a potential new risk biomarker in inflammatory bowel disease
Overall, we here disclosed a new mechanism underlying CAC development, identifying a potential clinical biomarker plausible to improve the efficacy of cancer surveillance programs through the early identification of high-risk IBD patients, for preventive clinical and therapeutic strategies.
Authors
- Catarina M. Azevedo (ORCID: https://orcid.org/0000-0003-1045-6485)
- Ricardo Marcos‐Pinto (ORCID: https://orcid.org/0000-0001-9695-8261)
- Ana M. Dias (ORCID: https://orcid.org/0000-0003-0060-2872)
- Carlos Taxonera (ORCID: https://orcid.org/0000-0001-9166-7350)
- Ângela Fernandes (ORCID: https://orcid.org/0000-0002-8255-5602)
- Beatriz Santos‐Pereira (ORCID: https://orcid.org/0000-0002-7094-0394)
- Isadora Rosa (ORCID: https://orcid.org/0000-0002-2953-5987)
- Salomé S. Pinho (ORCID: https://orcid.org/0000-0002-3484-5162)
- Eduarda Leite-Gomes (ORCID: https://orcid.org/0000-0002-5541-4759)
- María Jesús Fernández‐Aceñero (ORCID: https://orcid.org/0000-0002-2439-3553)
- Henrique Fernandes-Mendes
- Guilherme Faria (ORCID: https://orcid.org/0000-0003-1748-8762)
- Mariana Costa Silva (ORCID: https://orcid.org/0000-0002-1988-1093)
- Rafaela Nogueira (ORCID: https://orcid.org/0009-0009-3788-0121)
- Paula Lago
- Julian López Portero
- Joana Raposo
- Tania de Alda Catalá
Institutions
- Universidade do Porto (PT)
- Hospital Clínico San Carlos (ES)
- Hospital de Santo António (PT)
- Instituto Português de Oncologia de Coimbra Francisco Gentil (PT)
- i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto (PT)
Publication Details
- Journal
- Journal of Crohn s and Colitis
- Published
- 2025-03-15
- DOI
- https://doi.org/10.1093/ecco-jcc/jjaf043
- Citations
- 5
- Primary Topic
- Immunotherapy and Immune Responses
- Type
- article
- Field-Weighted Citation Impact
- 3.99