The prognosis prediction value of CD69+ CD8+ tissue-resident memory T cell as a novel indicator of pathologic complete response heterogeneity following different neoadjuvant therapy regimen in esophageal squamous cell carcinoma
The pCR obtained from different neoadjuvant treatments has distinct prognostic outcomes. The CD69 + CD8 + TRM, as a potential prognostic predictor, warrants further investigation.
Authors
- Yuanlin Li (ORCID: https://orcid.org/0000-0001-5466-6164)
- Dianxing Li
- Qiuan Yang (ORCID: https://orcid.org/0000-0002-1055-6753)
- Haiqun Lin (ORCID: https://orcid.org/0000-0002-3114-9671)
- Qiankun Wang (ORCID: https://orcid.org/0000-0003-2465-1468)
- Ao Liu (ORCID: https://orcid.org/0000-0003-4833-5718)
- Yi Li (ORCID: https://orcid.org/0000-0002-2928-1358)
- Xiuli Liu (ORCID: https://orcid.org/0000-0002-8243-5096)
- Minghuan Li
- Yaru Tian (ORCID: https://orcid.org/0009-0000-5962-6890)
- Longxiang Guo
- Jinming Yu (ORCID: https://orcid.org/0009-0006-5449-2356)
- Defeng Liu (ORCID: https://orcid.org/0000-0001-6372-4274)
- Yuxiang Chi
- Guobao Zheng
Institutions
- Shandong University (CN)
- Wenzhou Medical University (CN)
- Shandong Tumor Hospital (CN)
- Second Hospital of Shandong University (CN)
- Shandong Provincial Hospital (CN)
- Dongyang People's Hospital (CN)
- Qilu Hospital of Shandong University (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Cancer Immunology Immunotherapy
- Published
- 2025-03-15
- DOI
- https://doi.org/10.1007/s00262-025-03988-3
- Citations
- 2
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 2.09
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Shandong Province