Copy number variation at the complement C4 locus is associated with risk for multiple sclerosis
This finding suggests that lower C4 copies confer risk for MS, similar to associations seen in other autoimmune disorders.
Authors
- Jill A. Hollenbach (ORCID: https://orcid.org/0000-0001-6572-7962)
- Paul J. Norman (ORCID: https://orcid.org/0000-0001-8370-7703)
- Wesley M. Marin (ORCID: https://orcid.org/0000-0002-2334-0396)
- Danillo G. Augusto (ORCID: https://orcid.org/0000-0001-5665-8547)
- Kristen J. Wade (ORCID: https://orcid.org/0000-0002-0338-5028)
- Stacy J. Caillier (ORCID: https://orcid.org/0000-0002-0218-2077)
- Rayo Suseno
- Jacqueline Williams (ORCID: https://orcid.org/0000-0001-5978-5672)
- Kerry Kizer
Institutions
- University of North Carolina at Charlotte (US)
- University of California, San Francisco (US)
- University of Colorado Anschutz Medical Campus (US)
- Universidade Federal do Paraná (BR)
Publication Details
- Journal
- Multiple Sclerosis Journal
- Published
- 2025-03-15
- DOI
- https://doi.org/10.1177/13524585251324850
- Citations
- 2
- Primary Topic
- Complement system in diseases
- Type
- article
- Field-Weighted Citation Impact
- 1.59
Funders
- National Institute of Allergy and Infectious Diseases